Of course. Here is a summary of the provided personal accounts and insights regarding progesterone in hormone therapy.

Based on the shared experiences of many individuals, the decision to add progesterone is a personal one with potential benefits and considerations. While there is no one-size-fits-all answer, strong themes emerge from the community.

Potential Benefits of Adding Progesterone

Many people report significant positive changes after introducing progesterone, even years into their transition. These benefits often include enhanced breast development, such as a "growth spurt" or a "roundness improvement" that helps fill and shape the breasts. As one person shared, "Progesterone was very kind to me. I started after three years on E. Got breast buds again, got a growth spurt, and had a roundness improvement" – embracingaflowstate source. Other commonly reported benefits are improved mood stability, a more feminine experience of libido, and better body contouring as fat distribution becomes more rounded.

Commonly Discussed Timeline and Starting Point

The most frequently mentioned guideline within the community is to consider starting progesterone upon reaching Tanner stage 3 of breast development. This is the stage where initial breast buds have formed, and the belief is that progesterone can then help with rounding them out. One user noted, "I started progesterone around 9 months in as I had just gotten to tanner stage 3. I went from barely an A cup to pretty full B cups in the next 6 months" – WaterZealousideal535 source. If Tanner stage 3 isn't clearly reached, a common suggested minimum is about one year of stable estrogen therapy.

Acknowledging Variable and Personal Results

It is crucial to understand that experiences vary greatly. What works wonderfully for one person may have little effect or cause side effects for another. Some individuals are skeptical about its direct benefits, while others find it transformative. This variability is often attributed to the lack of extensive scientific research. As one user explained, "Otherwise, nobody knows if there even is such a thing as 'too early'. Literally not enough tests have been done, we have very little information on the matter" – rawayar source. Your own body's response will be unique.

Potential Side Effects to Monitor

While many have positive experiences, some report side effects. The most noted potential risk is the conversion of progesterone into DHT, a potent androgen, which could lead to effects like facial hair darkening or a receding hairline. One user shared, "I ended up stopping because it made my facial hair grow back almost twice as fast as it normally does" – DoubtDiary source. Others mention mood-related side effects, such as cyclical mood swings resembling pre-menstrual dysphoric disorder (PMDD) in those who are predisposed.

The Current State of Medical Evidence

The community is very aware that robust, large-scale studies on progesterone for transgender individuals are limited. While there are references to newer research, like a trial from Amsterdam UMC that found progesterone to be "safe and effective," most guidance is based on a small number of studies and a wealth of personal anecdotal evidence. This leads to a consensus that outcomes are highly individual.

In summary, the collective wisdom suggests that adding progesterone later in transition can be "worth it" for many, offering potential physical and emotional benefits. However, it is not a guaranteed step for everyone. The best path forward is to have an open and informed discussion with your healthcare provider, considering your personal goals, your body's development stage, and a willingness to monitor your individual response. This is your journey, and you have the power to explore what feels right for your body and your well-being.